Effects of Microgravity on Crystallizaion of Glucose Isomerase - Collaborative Studies toward the Proposal for Nanostep 2 Project -

Int. J. Microgravity Sci. Appl. 2014p124
Author
Y. SUZUKI, K. TSUKAMOTO, I. YOSHIZAKI, S. FUKUYAMA, M. TACHIBANA, H. KOIZUMI, T. FUJIWARA, H. SHIOZAWA, Y. UEHARA, T. SHIOMOTO and D. NAKAHASHI
Organization
Institute of Technology and Science, The University of Tokushima, Graduate School of Engineering, Osaka University, Japan Aerospace Exploration Agency, Advanced Engineering Services Co., Ltd., Graduate School of Nanobioscience, Yokohama City University, Institute for Materials Research, Tohoku University, Institute of Socio-Arts-and-Science, The University of Tokushima, Graduate School of Advanced Technology and Science, The University of Tokushima
Abstract
We focus on the growth mechanism of protein crystals and their perfection. The growth mechanism will be studied by surface observation and by measuring growth rates. Crystal defects will be studied by special etching and X-ray topography. We successfully carried out Nanostep experiments in 2012 using lysozyme crystals as model protein crystals. To generalize this result, a NanoStep2 experiment is planned to be flown in near future using glucose isomerase crystals. We need to obtain ground based data for the comparison with the Nanostep data. International collaboration is important to share a wide range of expertise for optimal scientific interpretation from different points of view.
Keyword(s)
crystal growth, surface morphology, growth rates, in situ observation
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